The Cheetah Conservation Fund’s (CCF) One Health Initiative will address multivariable needs of the communities that we work with. This new initiative will work to address the interconnected health of the people, their livestock and the free-living wildlife. Our initial focus for this initiative is rabies awareness and rabies prevention activities. According to the World Health Organization there are roughly 60,000 reported deaths from rabies, with the majority of the cases (95%) occurring in Asia and Africa, and 99% of transmission comes from domestic dogs. To face this very real threat the first activity under our One Health Initiative is a rabies awareness and vaccination campaign, focusing on the Hereroland communities in Eastern Namibia. Our awareness campaign began on World Rabies Day (September 28) in 2018, with the production and distribution of education materials. The second phase is the acquisition of a vehicle that will be outfitted and serve as the platform for a mobile vaccination clinic that will eventually provide spay/neuter procedures for companion animals. CCF’s Community Development and Veterinary teams will operate the mobile clinic to provide rabies prevention awareness education and free/low costs vaccinations for dogs and cats within the community, setting up a monthly calendar to provide education and services to maximize the impact for community members. By providing this service to these isolated communities CCF will reduce the risk of rabies transmission, save lives and protect both domestic and wildlife species. The goal of this project is to empower the communities to prevent rabies transmission and in the long term eradicate rabies in the region.